Recently, a French registry emphasized that poor in-hospital prognosis and more comorbidities were frequently associated with young females compared with males, while sex-related differences in mid- and long-term prognosis of premature coronary artery disease (PCAD) are less known. Importantly, relevant prior studies have been limited to small populations. Although the impact of gender on clinical outcomes after percutaneous coronary intervention (PCI) has been investigated in some studies, the issue remains complex and controversial. The onset age of CAD gets younger and younger in both developed and developing countries. However, CAD remains the leading cause of mortality and morbidity worldwide. IntroductionĬurrently, the mortality of coronary artery disease (CAD) is on the decline due in part to advancement of technology in cardiovascular medicine.
Despite remarkable differences in clinical characteristics between Asian males and females with PCAD, the two groups did not differ significantly in clinical outcomes. Young women were older and more likely to have hypertension and diabetes than men (all p0.05). Patients were followed up for three years and clinical outcomes were compared between groups. A total of 1397 Asian young patients with angiographically confirmed CAD undergoing drug-eluting stent implantation were included in this analysis and divided into two groups according to the genders. The present analysis aimed to evaluate the gender-related differences of PCAD in an Asian population from the FOCUS registry. Although coronary artery disease (CAD) presentations and clinical outcomes differ by sex, little is known about premature CAD (PCAD).
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